Improved survival with cytomegalovirus infection after intestinal transplantation in children.
نویسندگان
چکیده
I NTESTINAL transplantation (ITx) is now feasible with actuarial patient and graft survivals at 24 months exceeding 74% and 59%, respectively.l The occurrence of opportunistic infections such as cytomegalovirus (CMV), however, has significantly hindered further improvement in long term outcome. In this study, we focus upon our experience with CMV after ITx in children and analyze the influence of CMV infections upon postoperative outcome.
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OVER the last 5 years, intestinal transplantation has become a feasible therapeutic option for patients with irreversible intestinal failure. 1 Cytomegalovirus (CMv) infection was shown to be the most frequent viral infection in the intestinal transplant recipients and to be related to high mortality and morbidity.2.3 In this study, we analyzed the effect of CMv serology of donors and recipient...
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BACKGROUND Liver transplantation (LT) is a life-saving treatment for end-stage liver diseases (ESLD). Cytomegalovirus (CMV) infection is one of the important causes of morbidity after LT. OBJECTIVE To evaluate the incidence of late-onset (after 6 months of LT) CMV infection in pediatric recipients. METHODS A retrospective analysis was conducted to evaluate 50 pediatric patients who underwen...
متن کاملCurrent status of intestinal transplantation in children.
PURPOSE A clinical trial of intestinal transplantation (Itx) under tacrolimus and prednisone immunosuppression was initiated in June 1990 in children with irreversible intestinal failure and who were dependent on total parenteral nutrition (TPN). METHODS Fifty-five patients (28 girls, 27 boys) with a median age of 3.2 years (range, 0.5 to 18 years) received 58 intestinal transplants that incl...
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عنوان ژورنال:
- Transplantation proceedings
دوره 28 5 شماره
صفحات -
تاریخ انتشار 1996